Technical Data

044073
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_036214.2
Gene ID
23414
Gene #
ZFPM2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ZFPM2, CT (ZFPM2, FOG2, ZNF89B, Zinc finger protein ZFPM2, Friend of GATA protein 2, Zinc finger protein 89B, Zinc finger protein multitype 2)
ZFPM2, FOG2, ZNF89B, Zinc finger protein ZFPM2, Friend of GATA protein 2, Zinc finger protein 89B, Zinc finger protein multitype 2

The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ZFPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 882-911 amino acids from the C-terminal region of human ZFPM2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
De Luca, A., et al. Clin. Genet. (2010) In press :|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Hyun, S., et al. Cell 139(6):1096-1108(2009)|Rouf, R., et al. Circ. Res. 103(5):493-501(2008)|Bleyl, S.B., et al. Eur. J. Hum. Genet. 15(9):950-958(2007)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net