Technical Data

044096
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
O75844; NP_005848
Gene ID
10269
Gene #
ZMPSTE24
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ZMPSTE24, ID (ZMPSTE24, FACE1, STE24, CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog)
ZMPSTE24, FACE1, STE24, CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog

ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZMPSTE24.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Freije, J.M., et al., Genomics 58(3):270-280 (1999).|Kumagai, H., et al., Biochim. Biophys. Acta 1426(3):468-474 (1999).|Tam, A., et al., J. Cell Biol. 142(3):635-649 (1998).
USBio References
No references available
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