Technical Data

044140
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
O15231; NP_001171579.1
Gene ID
7739
Gene #
ZNF185
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ZNF185, NT (ZNF185, Zinc finger protein 185, LIM domain protein ZNF185, P1-A)
ZNF185, Zinc finger protein 185, LIM domain protein ZNF185, P1-A

Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ZNF185 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the N-terminal region of human ZNF185.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Zhang, J.S., et al. Oncogene 26(1):111-122(2007)|Medina, P.P., et al. Hum. Mol. Genet. 14(7):973-982(2005)|Vanaja, D.K., et al. Cancer Res. 63(14):3877-3882(2003)|Mallon, A.M., et al. Genome Res. 10(6):758-775(2000)|Heiss, N.S., et al. Genomics 43(3):329-338(1997)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net