Technical Data

044451
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C
Notes
Preservative Free
Rabbit Anti-ACE2 (SARS Receptor, Angiotensin-converting Enzyme 2, ACEH)

ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein corresponding to human ACE2.
Form
Supplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human ACE2. Detects a band of ~90kD by Western blot.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Product Reference: |●Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion: D.R. Beniac, et al.; PLoS One 2, e1082 (2007)|●
USBio References
No references available
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Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net