Rabbit Anti-PIP5K1C (KIAA0589, Phosphatidylinositol 4-phosphate 5-kinase Type-1 gamma, Phosphatidylinositol 4-phosphate 5-kinase Type I gamma)
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
MTPRHPLFTSRRPPAQPTRCARKAPAVEKPDPSPRSPARTHTPREQPLHSAQERGRPSSGTGQPRGSQHPSGQAHVGSSLRAQRVCPALGSDLGLSSQPGAHLLAPGIHPSAPALSLRRTPSRHPPGRQGQRSEGVSGTWMASRDRGIVISKAQPPEATPVLPGSPRVALPRALAPETPRACGVTRSSRCGPGRAAPRPGQPPSAE
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Full length human PIP5K1C, aa1-206 (AAH11138.1).
Form
Supplied as a liquid in PBS, pH 7.2.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PIP5K1C.
