Technical Data

131409
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG2a,k
Clone Number
1B2
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NM_001005476, NP_001005476
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-PKP4 (Plakophilin-4, p0071, FLJ31261, FLJ42243)

Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
EGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQ
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Partial recombinant corresponding to aa12-110 from PKP4 (NP_001005476) with GST tag. MW of the GST tag alone is 26kD.
Form
Supplied as a liquid in PBS, pH 7.2.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PKP4.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma. Teh MT, Ken Parkinson E, Thurlow JK, Liu F, Fortune F, Wan H.J Oral Pathol Med. 2010 Oct 4. doi: 10.1111/j.1600-0714.2010.00951.x. [Epub ahead of print]
USBio References
No references available
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