Technical Data

132476
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgM,k
Clone Number
4C2
Grade
Ascites
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NM_004726
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-REPS2 (POB1, RalBP1-associated Eps Domain-containing Protein 2, Partner of RalBP1, RalBP1-interacting Protein 2)

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
RVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGS
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Partial recombinant corresponding to aa66-166 from REPS2 (NP_004717) with GST tag. MW of the GST tag alone is 26kD.
Form
Supplied as a liquid in ascites fluid.
Purity
Ascites
Specificity
Recognizes human REPS2. Species Crossreactivity: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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