Mouse Anti-SNAPC 5 (Small Nuclear RNA Activating Complex Polypeptide 5 19kDa, snRNA Activating Protein Complex Subunit 5, SNAPc Subunit 5, SNAPC5, snRNA-activating Protein Complex 19kD Subunit, SNAPc 19kD Subunit, SNAP19) (APC)
SNAPC5 is a subunit of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC5 binds to the proximal sequence element (PSE) common to the promotor regions of these 2 types of genes, and recruits TBP and BRF2 to the U6 snRNA TATA box.
Applications
Suitable for use in FLISA and Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
MLSRLQELRKEEETLLRLKAALHDQLNRLKMLVHVDNEASINQTTLELSTKSHVTEEEEEEEEEESDS
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Full length recombinant corresponding to aa1-68 from SNAPC5 (AAH14315) with GST tag. MW of the GST tag alone is 26kD.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SNAPC5.
