UCP1

Clone Type

Monoclonal

Host

Mouse

Source

Human

Isotype

IgG2a,k

Clone Number

4B7

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Hu Mo

Accession #

NM_021833, NP_068605

Shipping Temp

Blue Ice

Storage Temp

-20°C

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Applications

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution

Optimal dilutions to be determined by the researcher.

AA Sequence

PVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAF

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Partial recombinant corresponding to aa232-267 from human UCP1 (NP_068605) with GST tag. MW of the GST tag alone is 26kD.

Form

Supplied as a liquid in PBS, pH 7.2.

Purity

Purified by Protein A affinity chromatography.

Specificity

Recognizes human UCP1. Species Crossreactivity: mouse.

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135055 Mouse Anti-UCP1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, Solute Carrier Family 25 Member 7, Thermogenin, SLC25A7, UCP)

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