Mouse Anti-CD54 (ICAM-1, Intercellular Adhesion Molecule 1, Human Rhinovirus Receptor, Precursor, BB2, Major Group Rhinovirus Receptor, P3.58)
Human CD54 (ICAM-1) mediates cell adhesion by binding to the integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). CD54 expression on resting peripheral blood leukocytes is weak but is upregulated on activated T and B lymphocytes and on monocytes.
Applications
Suitable for use in Flow Cytometry, Immunocytochemistry, Immunoprecipitation, ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Rheumatoid synovial cells and human monocytes
Form
Supplied as a liquid in BBS, pH 8.2.
Specificity
Recognizes human CD54. Species Crossreactivity: porcine
