Rabbit Anti-PTCH1 (Protein Patched Homolog 1, PTC, PTC1, PTCH)
Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KKINYQVDSWE, aa269-279, from mouse PTCH.
Purity
Purified by affinity chromatography.
Specificity
Recognizes mouse PTCH1. Species Crossreactivity: Human
