THETA is a tissue-specific mouse allo-antigen present in the highest concentrations in thymus and brain. Anti-THETA allo-antisera are produced after multiple injections of thymus cell suspensions into hosts differing at the THETA locus, but not at the principal histocompatibility locus (H-2). It is used to differentiate thymus derived lymphocytes from non-thymus derived lymphocytes, and to describe the relative role of each class of cells in various immunological functions.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.