Mouse Anti-Laminin (LAMA, Laminin a, LAMM, CLM, LIS5, LAMB1, LAMS, NPHS5, Laminin M chain, Laminin-12 subunit alpha, Laminin-2 subunit alpha, Laminin-4 subunit alpha, Merosin heavy chain, S-LAM beta)
Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1,beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260, 000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder.
UniProt Number
Human(P25391), Mouse(P19137), Rat(D4A409), Human(P24043), Mouse(Q60675), Rat(F1M614), Human(P07942), Mouse(P02469), Rat(D3ZQN7), Human(P55268), Mouse(Q61292), Rat(P15800)
Gene ID
LAMA1; LAMA2; LAMB1; LAMB2
Applications
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Paraffin sections Optimal dilutions to be determined by the researcher.
Storage and Handling
Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Form
Supplied as a liquid in1.2% sodium acetate, 5% BSA, 0.01% sodium azide.
Specificity
Recognizes human, feline and porcine Laminin. No cross reactivity with other proteins|