Mouse Anti-PSTAIR (CDC2, CDC28A, CDKN1, P34CDC2, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase)
The cyclin-dependent protein kinases (CDKs) regulate major cell cycle transitions in eukaryotic cells. CDKs contain an evolutionary conserved 16 amino acid sequence called PSTAIR (EGVPSTAIREISLLKE) which distinguishes them from other protein kinases. The PSTAIRE motif found in prototypic CDC2 kinases. CDC2L1 is referred as PITSLRE B, based on the amino acid sequence of the region corresponding to the conserved CDC2 PSTAIRE box.
UniProt Number
Human(P06493), Mouse(P11440), Rat(P39951)
Applications
Suitable for use in Western Blot.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Handling
Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic 16 amino acid oligopeptide containing the PSTAIR sequence conjugated to BSA.
Form
Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Specificity
Recognizes human and mouse PSTAIR. No crossreactivity with other proteins.