Rabbit Anti-DELTA-1 (Delta-like protein 1, Drosophila Delta homolog 1)
Delta-like protein 1 antibody, Drosophila Delta homolog 1 antibody
Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene. The notch signaling pathway has pleiotropic functions during mammalian embryogenesis. It is required for the patterning and differentiation of the presomitic and somitic paraxial mesoderm and of the neural tube. DLL1 is a human homolog of the notch delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis, and has been shown to have a role in cell-to-cell communication. Delta-like protein 1 would be sutiable for researchers in cell biology and signal transduction.
Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:3000-1:12,000 Western Blot: 1:100-1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa155-173 from mouse DELTA-1.
Form
Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes mouse DELTA-1. Species Crossreactivity: rat, human and chicken.