Rabbit Anti-PTGFR (PTGFR, PGF Receptor, PGF2-alpha Receptor, Prostaglandin F Receptor (FP), FP, PGF2 alpha Receptor, Prostaglandin F Receptor, Prostanoid FP Receptor)
The prostaglandin F2-alpha receptor is a member of the Prostanoid Receptor subfamily. Along with various other prostaglandin receptors, it mediates the effects of prostaglandin F(2-alpha) which include modulation of intraocular pressure, corpus luteum regression, and possibly uterine smooth muscle contraction. Alternative mRNA splicing gives rise to two isoforms, FP(A) and FP(B), that differ in their intracellular carboxyl termini and result in different mechanisms for receptor internalization.
Applications
Suitable for use in Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry (Formalin fixed paraffin embedded): 4-8ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to 16aa from 2nd extracellular domain of human PTGFR.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by immunoaffinity chromatography.|
Specificity
Recognizes human PTGFR. Species crossreactivity: gibbon, gorilla, equine and monkey.
