Rabbit Anti-PDE10A (5''-cyclic phosphodiesterase 10A, cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A, cAMP and cAMP-inhibited cGMP 3'', cAMP and cAMP-inhibited cGMP 3'5'-cyclic phosphodiesterase 10A, FLJ11894, HSPDE 10A, HSPDE10A, PDE 10A, PDE10_HUMAN, Pde10a, Phosphodiesterase 10A, Phosphodiesterase 10A1) (Not for Export EU)
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Applications
Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000. Predicted molecular weight: 88kD Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to amino acids in C-terminal of Human PDE 10A, common to the 10A enzyme
Form
Supplied as a liquid.
Specificity
Recognizes human PDE10A. Species Crossreactivity: mouse and rat
