Rabbit Anti-PIP1 (PAK-Interacting Protein, PAK1IP1, WD Repeat-containing Protein 84, WDR84, PIP-1, PIP 1) (Biotin)
The family of p21-activated protein kinases (PAKs) is composed of serine-threonine kinases. A novel human PAK-interacting protein, hPIP1, interacts with PAK1 and inhibits the Cdc42/Rac-stimulated kinase activity suggesting that hPIP1 is a negative regulator of PAK and PAK signaling pathways.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human PIP-1.
