Rabbit Anti-Interleukin-36 Receptor antagonist (HRP)
FIL1 delta,IL-1-related protein 3,Interleukin-1 HY1,Interleukin-1 delta,Interleukin-1 family member 5,Interleukin-1 receptor antagonist homolog 1,Interleukin-1-like protein 1,FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3,UNQ1896/PRO4342,IL36RN
Is a highly and a specific antagonist of the IL-1 receptor-related protein 2/IL1RL2-mediated response to interleukin IL36G. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant human Interleukin-36 receptor antagonist protein (aa1-155).
Form
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with horseradish peroxidase (HRP)
Purity
Purified by Protein G affinity chromatography.
