Rabbit Anti-YME1L1 (FTSH1, YME1L, ATP-dependent Zinc Metalloprotease YME1L1, ATP-dependent Metalloprotease FtsH1, Meg-4, Presenilin-associated Metalloprotease, YME1-like Protein 1)
FTSH1, YME1L, ATP-dependent Zinc Metalloprotease YME1L1, ATP-dependent Metalloprotease FtsH1, Meg-4, Presenilin-associated Metalloprotease, YME1-like Protein 1
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
Applications
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Form
Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human YME1L1. Species Crossreactivity: mouse and rat
