Rabbit Anti-KOX17 (KOX17, Retinoic acid suppression Protein A, RSG A, RSGA, Zfp191, Zinc Finger and SCAN Domain Containing Protein 3, Zinc Finger Protein 191, Zinc Finger Protein 24, Zinc Finger Protein KOX17, ZNF 24, ZNF191, ZSCAN 3, ZSCAN3)
Zinc finger protein 18, Zinc finger protein KOX11, Heart development-specific gene 1 protein, Zinc finger protein with KRAB and SCAN domains 6, ZNF18
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence By similarity. Has transcription repressor activity in vitro.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:500-1:3000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to N-terminal of human ZNF24.
Form
Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ZNF24. Species Crossreactivity: mouse and rat
