Technical Data

352623
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu Mo
Accession #
NP_003960.1, NP_663553.1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-UBC12, CT (Ubiquitin Conjugating Enzyme E2M, NEDD8-Conjugating Enzyme Ubc12, NEDD8 Carrier Protein)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Positive Control
Mouse Liver Tissue Lysate
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Peptide corresponding to human and mouse UBC12 at C-terminal. Species sequence homology: UBC12 from other mammalian species
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity
Purified by affinity chromatography.
Specificity
Recognizes UBC12. Species Crossreactivity: human and mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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