Technical Data

378612
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-RLBP1, CT
Retinaldehyde-binding protein 1, Cellular retinaldehyde-binding protein, RLBP1, CRALBP|

Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within aa255-288 from human RLBP1.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human RLBP1. Species Crossreactivity: mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Crabb J.W.,et al.J. Biol. Chem. 263:18688-18692(1988).|2. Intres R.,et al.J. Biol. Chem. 269:25411-25418(1994).|3. Ota T.,et al.Nat. Genet. 36:40-45(2004).|4. Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.|5. Crabb J.W.,et al.Protein Sci. 7:746-757(1998).
USBio References
No references available
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