Rabbit Anti-PIK3R3 (Phosphatidylinositol 3-Kinase Regulatory Subunit Gamma, PI3-Kinase Regulatory Subunit Gamma, PI3K Regulatory Subunit Gamma, PtdIns-3-Kinase Regulatory Subunit Gamma, Phosphatidylinositol 3-Kinase 55kD Regulatory Subunit Gamma, PI3-Kinase Subunit p55-Gamma)
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Applications
Suitable for use in ELISA, Immunohistochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein corresponding to aa1-230 of human PIK3R3.
Form
Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human PIK3R3.
