Mouse Anti-AES (AES-1, AES-2, ESP1, GRG, GRG5, TLE5)
The protein encoded by this gene is similar in sequence to the N-terminal of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
MCHKNGFPQEGGITAAFLQKRKLRLSKNHRPARAKVT EHVRGTRPGRATAGPAASTRAAGSLFFDRWGNRGPA GCRGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSL KLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQA EIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAP ELNSIIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPA VSAGTGLLSLSALGSQAHLSKEDKNGHDGDTHQEDD GEKSD
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Protein corresponding to aa1-264 from full length human AES.
Form
Supplied as a liquid in PBS, pH 7.4.
Specificity
Recognizes human AES.
