The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGA EHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEV QGVRVSGLPRYDVLGVIDSCKEAVTFKAVRQGGRLNK DLRHFLNQRFQKGSPDHELQQTIRDNLYRHAVPCTTR SPREGEVPGVDYNFLTVKEFLDLEQSGTLLEVGTYEG NYYGTPKPPSQPVSGKVITTDALHSLQSGSKQSTPKR TKSYNDMQNAGIVHAENEEEDDVPEMNSSFTADSGE QEEHTLQETALPPVNSSIIAAPITDPSQKFPQYLPLSAE DNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRC LNKQQKPLEECEDDEGVHTEELDSELELPAGWEKIED PVYGIYYVDHINRKTQYENPVLEAKRKKQLEQQQQQQ QQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPP SNPEPAREVPLQGKPFFTRNPSELKGKFIHTKLRKSSR GFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGD VIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGY PLPFDPDDPNTSLVTSVAILDKEPIIVNGQETYDSPASH SSKTGKVNGMKDARPSSPADVASNSSHGYPNDTVSL ASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVK QIVDSPRCRGLKEGDLIVEVNKKNVQALTHNQVVDML VECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQN SSQHSVSSHRSLHTASPSHSTQVLPEFPPAEAQAPDQ TDSSGQKKPDPFKIWAQSRSMYENRPMSPSPASGLS KGEREREINSTNFGECPIPDYQEQDIFLWRKETGFGFR ILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDG TPVIGKSHQLVVQLMQQAAKQGHVNLTVRRKVVFAVP KTENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLN TVSSGSGSTSGIGSGGGGGSGVVSTVVQPYDVEIRR GENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRI IEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIK EAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHTPSQQ GTQETRNTTKPKQESQFEFKAPQATQEQDFYTVELER GAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKM RIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKR GDGSVPEYGGSNYENIPSFPGMTP
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Protein corresponding to aa 1-1256 from full length human MAG11
Form
Supplied as a liquid in PBS, pH 7.4.
Specificity
Recognizes human MAG11
TDS
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UniProt
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