Technical Data

552560
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
6B9G10
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-CD102
ICAM2

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins contain 2-9 immunoglobulin-like C2-type domains and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.

Applications
Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified recombinant protein fragment corresponding to aa25-223 from human CD102, expressed in E. coli.
Form
Supplied as a liquid in PBS, 0.05% sodium azide.
Purity
Purified
Specificity
Recognizes human CD102.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Curr Opin Hematol. 2015 Jan;22(1):53-9. |2. BMC Cancer. 2013 May 28;13:261.
USBio References
No references available
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