Technical Data

553898
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
56.7D7
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-Thyroglobulin

Thyroglobulin is a ~660kD homodimer produced by the thyroid gland, specifically in the thyrocytes, and stored within the follicular lumen. Thyroglobulin is the precursor of the iodated thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones affect protein, fat and carbohydrate metabolism. Defects in thyroglobulin production can lead to goiter, and increased susceptibility to autoimmune thyroid type 3 diseases, such as Graves disease and Hashimoto thyroiditis.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:10,000-1:100,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography from tissue culture supernatant.
Specificity
Recognizes human Thyroglobulin.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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