Technical Data

A2275-79-ML550
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
MaxLight™550
Isotype
IgG
Grade
Affinity Purified
Applications
DB FLISA IHC RIA
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
BSA Free
Rabbit Anti-β-Amyloid, pan (MaxLight 550)
Applications
Suitable for use in RIA, FLISA, Dot Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide corresponding to aa1-40 of human b-Amyloid
Form
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™550.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes the sequence of human b-Amyloid [1-40] in the region from amino acids 15-30. No blocking activity was observed with b-Amyloid [1-12], whereas the peptides b-Amyloid [14-35], b-Amyloid [15-28] and b-Amyloid [17-30] were all able to block antibody activity as well as b-Amyloid [1-40].

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. DeMattos, R.B., et al., J. Neurochem. 81(2): 229-236 (2002). 2. Fagan, A.M., et al., Neurobiol. Dis. 9(3): 305-318 (2002). 3. DeMattos, R.B., et al., Proc. Natl. Acad. Sci. USA 98(15): 8850-8855 (2001). 4. Savage, M.J., et al., J. Neurosci. 18: 1743-1752 (1998). 5. Borchelt, D.R., et al., Neuron 19: 939-945 (1997).
USBio References
No references available
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