Mouse Anti-Antithrombin III (AT3, ATIII, AT-III, Antithrombin, Heparin Co-factor 1, MGC22579, Serine (or cysteine) Proteinase Inhibitor Clade C (Antithrombin) Member 1, SERPIN C1, Serpin Peptidase Inhibitor Clade C (Antithrombin) Member 1)
SERPINC1 is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Full-length recombinant protein corresponding to amino acid 1-259 of human Antithrombin III.
Form
Supplied as a liquid in PBS, pH 7.4.
Specificity
Recognizes human Antithrombin III.
