Rabbit Anti-APRIL (A Proliferation Inducing Ligand, CD256, CD256 Antigen, PRO715, Proliferation Inducing Ligand APRIL, TNF and APOL-related Leukocyte Expressed Ligand 2, TALL 2, TALL2, TALL-2, Tumor Necrosis Factor Related Death Ligand, Tumor Necrosis Factor Related Death Ligand 1, TNF-related Death Ligand 1, TRDL 1, TRDL1, TRDL-1, Tumor Necrosis Factor (Ligand) Superfamily Member 13, Tumor Necrosis Factor Ligand Superfamily Member 13, TNFSF13, TNFSF13 Protein, TWE PRIL, TWE-PRIL, UNQ383, UNQ383/PRO715, ZTNF2)
CD256 is a member of the tumor necrosis factor family, which is expressed in B cells and several tumor cells. The protein is involved in stimulating B and T cell proliferation, triggering humoral immune responses, activating NF-kappaB and inducing cell death. CD256 is thought to play a role in autoimmune diseases and cancer.
Applications
Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1-4ug/ml Immunohistochemistry (paraffin): 1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa196-210 of human CD256.
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human CD256. Species Crossreactivity: rat and mouse.