Technical Data

A3570-66P1
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_076447
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Arhgef9, ID (Rho Guanine Nucleotide Exchange Factor 9, Rac/Cdc42 Guanine Nucleotide Exchange Factor 9, Collybistin, PEM-2 Homolog, KIAA0424)

ARHGEF9 belongs to a family of Rho-like GTPases that act as molecular switches by cycling from the active GTP-bound state to the inactive GDP-bound state. These proteins are key regulators of the actin cytoskeleton and are involved in cell signaling.

Applications
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide located between amino acids 281-311 of rat Arhgef9 (conjugated to KLH)
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human Arhgef9.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Xiang,S., J. Mol. Biol. 359(1), 35-46 (2006). 2. Harvey,K., J. Neurosci. 24(25), 5816-5826 (2004). 3. Grosskreutz,Y., Biol. Chem. 382(10), 1455-1462 (2001). 4. Kins,S., Nat. Neurosci. 3(1), 22-29 (2000).
USBio References
No references available
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