Technical Data

B2553-52A
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_005439
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-BMP15, ID (Bone Morphogenetic Protein 15, BMP-15, Growth/Differentiation Factor 9B, GDF-9B, GDF9B)

Bmp15 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that Bmp15 may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9.

Applications
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the Center region of human BMP15 (KLH).
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human BMP15.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Liao, W.X., et al., J. Biol. Chem. 278(6):3713-3719 (2003). 2.Moore, R.K., et al., J. Biol. Chem. 278(1):304-310 (2003). 3.Galloway, S.M., et al., Nat. Genet. 25(3):279-283 (2000). 4.Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84(8):2744-2750 (1999). 5.Dube, J.L., et al., Mol. Endocrinol. 12(12):1809-1817 (1998).
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net