Mouse Anti-Catenin, delta 2 (Neural Plakophilin-related ARM-repeat Protein, NPRAP, Neurojungin, GT24, CTNND2)
Delta-catenin, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, GT24, GENE NAME: CTNND2
Catenin delta-2 functions as a transcriptional activator when bound to ZBTB33. It may also be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. It is predominantly expressed in the brain and localises to the nucleus and cell junction. The unprocessed precursor has a length of 1225 amino acids and a predicted molecular weight of 132.7KDa. This protein is O-glycosylated. It is also phosporylated upon DNA damage. It belongs to the beta-catenin family and contains nine ARM repeats.
Applications
Suitable for use in Immunohistochemistry and Western Blot . Other applications not tested.
Recommended Dilution
Optimal dilution determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Partial recombinant protein of human catenin delta-2 (aa1081-1190) with a GST tag.
Form
Supplied as a lyophilized powder in PBS, pH7.2. Reconstitute with 100ul sterile ddH2O.
Purity
Purified by affinity chromatography.
Specificity
Recognizes human Catenin delta 2. Species Crossreactivity: mouse and rat.
