The CD38 antigen is also known as T10 antigen. The CD38 antigen is a 45kD single-chain type II glycoprotein., It is an integral membrane protein with a long extracellular C-terminal domain, a single membrane-spanning region and a short N-terminal cytoplasmic tail. The CD38 antigen is expressed on a variety of hematopoietic cells. Its distribution depends on the state of the cell differentiation and the cell activation. In adults, the CD38 molecule is expressed on earlier stage of B lymphocyte ontogeny, lost during maturation and re-expressed upon terminal differentiation to plasma cells. This molecule is also strongly expressed on thymocytes. It is found at low density on resting T lymphocytes. It is expressed on the majority of resting NK cells and monocytes. It is also found on platelets and red blood cells.

Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested.

Flow Cytometry: 1:100. Use 10ul to label 10e6 cells in 100ul. Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher.

NS1 myeloma cells with spleen cells from Balb/c mice.

Mouse IgG1 Negative Control

F(ab')2 rabbit anti-mouse IgG HRP F(ab')2 rabbit anti mouse IgG: RPE conjugate

May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile (40-50% ) glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Note: Applications are based on unconjugated antibody.

CD38

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.

Purified by Protein A affinity chromatography.

Recognizes human CD38 a 45kD glycoprotein and has a reactivity pattern consistent with antibodies of the CD38 cluster. CD38 is expressed by plasma cells, monocytes, early lymphoid cells and activated T cells.