Mouse Anti-CD57 (HNK-1, NK (Natural Killer) Cells)
Human CD57 originally called HNK-1 is a glycoprotein found on 15-20 percent of PBL's, including 60 percent of NK cells, and a subset of T cells (1). The immune regulation role of CD57 postive PBL's expressing high levels of CD8 is being investigated (2).
Applications
Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Human peripheral blood mononuclear cells
Form
Supplied as a liquid in PBS, pH 7.2, 5% glycerol, 0.2% BSA, 0.05% sodium azide.
Purity
Purified immunoglobulin (95%).
Specificity
Recognizes the CD57 molecule of about 110kD.
