Mouse Anti-CD61 (Glycoprotein IIIa, Integrin beta3) (MaxLight 650)
Platelet glycoprotein IIIa, ITGB3, GP3A
MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000.
CD61 (Glycoprotein IIIa, GPIIIa, Integrin beta3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronection, von Willebrand factor and vitronectrin.
Applications
Suitable for use in Flow Cytometry, Western Blot and Blocking studies. Other applications not tested.
Recommended Dilutions
Western Blot: Reducing conditions Blocking: Blocks Integrin beta3-mediated adhesion to ECM proteins. Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Human Integrin alphaVbeta3 heterodimer isolated from placenta
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Specificity
Recognizes human Integrin beta 3.
