Mouse Anti-CD61 (Glycoprotein IIIa, Integrin beta3)
Platelet glycoprotein IIIa, ITGB3, GP3A
CD61 (Glycoprotein IIIa, GPIIIa, Integrin beta3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronection, von Willebrand factor and vitronectrin.
Applications
Suitable for use in Flow Cytometry, Western Blot and Blocking studies. Other applications not tested.
Recommended Dilutions
Western Blot: Reducing conditions Blocking: Blocks Integrin beta3-mediated adhesion to ECM proteins. Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Human Integrin alphaVbeta3 heterodimer isolated from placenta
Form
Supplied as a liquid in PBS. No preservatives added.
Specificity
Recognizes human Integrin beta 3.
