Rabbit Anti-CD79a (B Cell)
A disulfide-linked heterodimer, consisting of CD79a / mb-1 and CD79b / B29 polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas.
Applications
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry (Formalin/paraffin): 1:50-1:150 for 30 min. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to the N-terminal region of human CD79a protein. Cellular Localization: Cell membrane
Form
Supplied as a liquid in 15mM sodium azide.
Purity
Culture supernatant
Specificity
Recognizes human CD79a. Does not react with mouse, rat, canine, monkey, opossum.
