Mouse Anti-CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1, INCAM-110)
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Applications
Suitable for use in Function Blocking. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Form
Supplied as a liquid in 0.2M PBS, pH 7.6, 0.09% sodium azide
Specificity
Recognizes the human VCAM-1 molecule. Inhibits VLA-4 (integrin a4b1) binding.
