Technical Data

C2453-01J
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
GIR-208
Grade
Affinity Purified
Applications
FC IP WB
Crossreactivity
Hu
Gene ID
3459
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-CD119 (Interferon gamma Receptor 1, IFN-gamma Receptor 1, IFN-gamma-R1, IMD27, IFNGR1)

CD119 (alpha subunit of interferon gamma receptor) is a type I transmembrane glycoprotein, which associates with IFNgammaAF1 to form functional receptor for interferon gamma, although CD119 alone is able to bind the cytokin. It is expressed on monocytes, macrophages, lymphocytes, NK cells, neutrophils, fibroblasts, epithelial and endothelial cells, as well as in many tumors.

Applications
Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilution
Flow Cytometry: 1-4ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CD119 purified from human placenta
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CD119.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Sheenan KC, Calderon J and Schreiber RD. Generation and characterization of monoclonal antibodies specific for the human IFN-gamma receptor. J Immunol. 1988 Jun 15;140(12):4231-7.
USBio References
No references available
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