Mouse Anti-cdk7 (BSA, Azide Free) (Cyclin-dependent Kinase 7)
CAK1, STK1, CDKN7, p39MO15
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Applications
Suitable for use in Flow Cytometry, Dot Blot, Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested.
Recommended Dilution
Flow Cytometry: 0.5-2ug/sample Western Blot: 0.2-2ug/ml Immunocytochemistry: 2-100ug/ml Immunoprecipitation: 100-500ug/sample Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Partial recombinant protein corresponding to a portion of human cdk7.
Form
Supplied as a liquid in PBS, pH 7.4. No stabilizing proteins added. No preservative added.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human cdk7.
