Technical Data

C2617-02B3
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC
Crossreactivity
Hu
Accession #
NP_060874.1
Gene ID
55803
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-CENTA2 (Arf-GAP with Dual PH Domain-containing Protein 2, Centaurin-alpha-2, Cnt-a2, ADAP2)

Centaurin alpha 2 is a potential GTPase-activating protein for the ADP ribosylation factor family. It binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). It possesses a stoichiometry of two binding sites for InsP4 with identical affinity.

Applications
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:32,000 Immunohistochemistry (Paraffin): 5-10ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-RLTASTESGRSSR, from human ADAP2, at C-terminal (NP_060874.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ADAP2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Jenne DE, Tinschert S, Stegmann E, Reimann H, N]urnberg P, Horn D, Naumann I, Buske A, Thiel G. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. Genomics. 2000 May 15;66(1):93-7.
USBio References
No references available
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