Rabbit Anti-Collagen Type XVII (BP180, Collagen type XVII alpha 1, COL17A1, 180kD bullous pemphigoid antigen 2, BA16H23.2, BPAG2, Bullous pemphigoid antigen 2, Collagen alpha-1(XVII) chain, FLJ60881, KIAA0204, LAD-1)
COL18A1 is encoding the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein.
Applications
Suitable for use in Immunohistochemistry Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Staining of type XVII collagen in frozen sections of mouse skin. Optimal dilutions to be determined by the researcher.
Positive Control
Mouse skin
Storage and Stability
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Recombinant protein corresponding to aa497-573 from mouse Collagen Type XVII with GST-fusion protein.
Form
Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with sterile ddH2O to a concentration of 1mg/ml.
Purity
Purified by Protein G affinity chromatography
Specificity
Recognizes mouse Type XVII Collagen. Stains skin and hair follicle basement membrane.
