Technical Data

C9096-05D
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004279.3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-CYTIP (PSCDBP, Cytohesin-interacting Protein, Cytohesin Binder and Regulator, CYBR, Cytohesin-associated Scaffolding Protein, CASP, Cytohesin-binding Protein HE, Cbp HE, Pleckstrin Homology Sec7 and Coiled-coil Domains-binding Protein)
pleckstrin homology, Sec7 and coiled/coil domains, binding protein, pleckstrin homology, Sec7 and coiled-coil domains, binding protein, cytohesin binder and regulator, cytohesin 1 interacting protein, pleckstrin homology, Sec7, and coiled-coil domains protein-binding protein, cytohesin-1 interacting protein, cytohesin binding protein HE, CASP, B3-1, HE, pleckstrin homology, Sec7 and coiled/coil domains, binding protein, CYBR, PSCDBP, CYTIP

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.

Applications
Suitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:16,000 Western Blot: 1-3ug/ml detects ~38kD band observed in lysates of cell line MOLT4 (calculated MW of 40.0kD according to NP_004279.3) Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to SLQRLLQHSSNGN-C, from the N Terminus of human CYTIP (NP_004279.3).
Form
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes human CYTIP.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. The goat polyclonal antibody used in this paper was manufactured by us:O'Brien M, Morrison JJ, Smith TJ.Upregulation of PSCDBP, TLR2, TWIST1, FLJ35382, EDNRB, and RGS12 gene expression in human myometrium at labor.Reprod Sci. 2008 Apr;15(4):382-93.
USBio References
No references available
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