Technical Data

D1559-93
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Ca Hu Mo
Accession #
NP_076955.1
Gene ID
79016, 66498
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-DDA1 (DET1- and DDB1-associated Protein 1, Placenta Cross-immune Reaction Antigen 1, PCIA-1, C19orf58, PCIA1)

May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:32,000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-PSVYLPTREYP, from DDA1, at the internal region of the protein (NP_076955.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes DDA1. Species sequence homology: Canine, human and mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Olma MH, Roy M, Le Bihan T, Sumara I, Maerki S, Larsen B, Quadroni M, Peter M, Tyers M, Pintard L, An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases. J Cell Sci. 2009 Apr 1;122(Pt 7):1035-44.
USBio References
No references available
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