Rabbit Anti-DR3 (Wsl-1, Apo-3, TRAMP, LARD1-5, Death Receptor3) (PE)
DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).The ligand for DR3 has very recently been identified and has been termed Apo-3L.DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD and functionally induces apoptosis and NF-KB activation.
Applications
Suitable for use in Western Blot. Other applications have not been tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Peptide sequence corresponding to QGGTRSPRCDCAGDFH from the N-terminus of human DR3
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Purity
Purified by ion exchange chromatography.
Specificity
Recognizes human DR3.
