Rabbit Anti-DUSP13 (Dual Specificity Phosphatase 13, BEDP, Dual Specificity Phosphatase SKRP4, FLJ32450, MDSP, Testis-and Skeletal-muscle-specific DSP, TMDP)
DUSP13, a novel DSP, is a member of highly conserved Protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation. DUSP13 consists of a conserved catalytic domain and is expressed specifically in the testis and skeletal muscle. Based on mRNA localization and expression studies during development, DUSP13 is suggested to be expressed as 3 isoforms due to alternative splicing. Reports suggest DUSP13 might be involved in the regulation of meiosis and differentiation of testicular germ cells during spermatogenesis.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 0.5-2ug/ml Optimal dilutions to be determined by the researcher.
Positive Control
Human skeletal muscle lysate
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa150-200 of human DUSP13.
Form
Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Purity
Purified by Protein G affinity Chromatography.
Specificity
Recognizes human DUSP13 (isoforms 1, 2 and 3). Species Crossreactivity: bovine, chimpanzee, canine, rhesus monkey. Species sequence homology: mouse and rat.
