Technical Data

D9901-51
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_001367.2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Goat Anti-Dynein (Cytoplasmic 1, Heavy Chain 1, DYNC1H1)
dynein, cytoplasmic-like, dynein, cytoplasmic, heavy polypeptide 1, dynein heavy chain, cytosolic, cytoplasmic dynein heavy chain, DYNC1H1 variant protein, p22, KIAA0325, HL-3, Dnchc1, DYHC, DNECL, DNCL, DNCH1, DKFZp686P2245, DHC1a, DHC1, dynein, cytoplasmic 1, heavy chain 1, DYNC1H1

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.

Applications
Suitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
ELISA (Peptide): 1:4000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-EKKTRTDSTSDGRP, from the internal region of human DYNC1H1.
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes human DYNC1H1. Species Sequence Homology: rat

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Chen XJ, Levedakou EN, Millen KJ, Wollmann RL, Soliven B, Popko B Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene J Neurosci. 2007 Dec 26;27(52):14515-24
USBio References
No references available
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