E9005-08D
Clone Type
PolyclonalHost
RabbitSource
RatIsotype
IgGGrade
Affinity PurifiedApplications
WBCrossreactivity
RtShipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-Exodus 2 (SLC, Secondary Lymphoid-tissue Chemokine, 6Ckine, TCA4)
SLC (secondary lymphoid-tissue chemokine, also called 6Ckine, TCA4, Exodus-2) is a 111aa (human; 110aa for mouse) CC chemokine with an NH2-terminal sequence of 23 residues as a signal sequence. It was originally cloned in 1997. Recombinant SLC attracts T-, B- cells, mature dendritic cell, but did not induce any cell migration in neutrophils or monocytes. SLC is a functional ligand for CCR7.
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:5000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
E. coli-expressed rat SLC
Form
Supplied as a liquid, 0.05% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes rat Exodus 2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Hedreck, J.A., et al. (1997) J Immunol. 159:1589-1593. 2. Tanabe, S., et al. (1997) J Immunol. 159:5671-5679. 3. Yoshie, O. et al. (1997) J Leukoc Biol. 62:634-644. 4. Chan, V.W., et al. (1999) Blood. 93:3610-3616. 5. Campbell, J.J., et al. (1998) J Cell Biol. 141:1053-1059.USBio References
No references available